基于真实脑模型的锥形经颅磁磁芯线圈研究

      Optimal design of transcranial magnetic stimulation cone coil and X-shaped magnetic core

      • 摘要: 为探究经颅磁刺激(transcranial sagnetic stimulation, TMS)线圈穿透性能和聚焦性能提升相互矛盾的问题,提出了一种新型锥形线圈以提高浅层线圈的聚焦性,并加入X形磁芯进一步提升整体线圈的穿透性能和聚焦性能,以解决线圈各性能提升的矛盾性。选择两组类8字形线圈结构组成组合线圈,以更好地加入X形磁芯。并对比不同的电流激励方式及线圈形状,选择出最优的组合线圈模型。最后对不同高度、宽度、厚度的X形磁芯分别从刺激深度及聚焦性2个方面进行分析。对于锥形线圈,选用三角8字形线圈可以有效增加聚焦性能;选用合适参数的X形磁芯,聚焦性能提升约8.67%,穿透性能提升约18.72%,可显著提升在头皮处产生的电场的聚焦性及穿透性。新型锥形线圈可为与后续脑区功能障碍相关的精神和神经疾病的研究和临床应用提供一个新的工具。

         

        Abstract: To explore the conflicting requirements of enhancing both the penetration depth and focusing precision of transcranial magnetic stimulation (TMS) coils, a novel conical coil design is proposed. This innovative approach seeks to improve the focusing capabilities for shallow-depth stimulation while simultaneously maintaining or enhancing penetration depth. Meanwhile, an X-shaped magnetic core was incorporated to further enhance the penetration and focusing performance of the overall coil, thereby resolving the contradictions in the performance improvement of the coils. Two sets of class 8 coil structures were selected to form a combined coil to better fit the X-core. The effects of different current excitation methods and coil shapes were compared, and the optimal combined coil model was selected. Finally, based on the feature that the X-core has variable height, width, and thickness, the stimulation depth and focusing properties of the X-core with different height, width, and thickness were analyzed separately from two aspects. The results of the optimal core coil were compared with those of the previously proposed superficial stimulation coil. For conical coils, the selection of triangular figure of eight(FOE)首次出现加全拼 coils can effectively enhance the focusing performance. And for adjacent coils in the conical coil configuration with opposite current directions, significant improvements in focusing performance were observed. By carefully selecting appropriate parameters for the X-shaped magnetic core, a notable enhancement in both the focusing and penetration capabilities of the electric field generated at the scalp was achieved. Specifically, the focusing performance improved by approximately 8.67%, while the penetration performance increased by approximately 18.72%. The use of a conical transcranial magnetic stimulation (TMS) coil with properly chosen parameters for the X-shaped magnetic core can simultaneously enhance the focusing and penetration capabilities. This development may offer a novel tool for studying and clinically applying treatments related to mental and neurological disorders associated with subsequent brain area dysfunctions.

         

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